NUDT1 / MTH1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.

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Products

Proteins (24)

Type

Over-Expression Lysate (13)

Recombinant (11)

Target

NUDT1 / MTH1 (24)

Publications

No (24)

Tag

10His, N-terminus (1)

6His, N-terminus (1)

GST (1)

His (1)

Myc-DDK (Flag) (19)

Species

Human (18)

Source

293T Cells (7)

Baculovirus (1)

E. coli (2)

HEK 293 Cells (12)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (4)

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Human NUDT1 / MTH1 Protein (Recombinant His) - LS-G964

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human NUDT1 / MTH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64803

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$1,107

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Human NUDT1 / MTH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64804

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$1,107

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Human NUDT1 / MTH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64805

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.1 kDa

Price:

20 µg/$1,107

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Human NUDT1 / MTH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64807

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.1 kDa

Price:

20 µg/$1,107

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Human NUDT1 / MTH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64806

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$1,107

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Human NUDT1 / MTH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64808

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$1,107

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74236

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74237

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74240

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.1 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74238

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74241

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74244

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74247

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.1 kDa

Price:

20 µg/$150

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Human NUDT1 / MTH1 Protein (Recombinant GST) (Full Length) - LS-G29397

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.43 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NUDT1 / MTH1 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G136846

Source:

Baculovirus

Tag:

10His, N-terminus

Molecular Weight:

22.8 kDa

Price:

100 µg/$920; 20 µg/$411; 1 mg/$1,808

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Human NUDT1 / MTH1 Protein (Recombinant) (Full Length) - LS-G137080

Source:

E. coli

Tag:

None

Molecular Weight:

20.3 kDa

Price:

1 mg/$1,568; 100 µg/$534; 20 µg/$422

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Human NUDT1 / MTH1 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G136599

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

22.3 kDa

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117969

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

100 µg/$494

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NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103401

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

100 µg/$494

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NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103402

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.1 kDa

Price:

100 µg/$494

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NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103405

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

100 µg/$494

Select

NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103404

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

100 µg/$494

Select

NUDT1 / MTH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103406

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.1 kDa

Price:

100 µg/$494

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