NUDT1 / MTH1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.

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ELISA Kits (4)

Type

Custom (1)

Sandwich (3)

Target

NUDT1 / MTH1 (4)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

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Mouse NUDT1 / MTH1 (Sandwich ELISA) ELISA Kit - LS-F19833

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat NUDT1 / MTH1 (Custom ELISA) ELISA Kit - LS-F19832

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human NUDT1 / MTH1 (Sandwich ELISA) ELISA Kit - LS-F32598

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human NUDT1 / MTH1 (Sandwich ELISA) ELISA Kit - LS-F10690

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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