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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NTSR1 / NTR

neurotensin receptor 1 (high affinity)

NTR1, a Neurotensin Receptor, activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems. It mediates the functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Neurotensin Receptor 1 expression is enhanced in pancreatic cancer and in chronic pancreatitis (Wang et al, 2000). Two differentially glycosylated forms of the NT1 receptor have been identified in rats, a 54-kD form that is expressed from birth to adulthood, and a 52-kD form only detected at 10 and 15 days postnatal.

Gene Name: neurotensin receptor 1 (high affinity)
Family/Subfamily: GPCR , Neurotensin
Synonyms: NTSR1, Neurotensin receptor type 1, NT-1r, NT1 receptor, NTR, NTS1, Neurotensin receptor 1, NT-R-1, NTR1, NTRH, NTRR, Neurotensin receptor ntr1, NTS-1, Neurotensin type 1 receptor, NT receptor-1, RNTR1
Target Sequences: NM_002531 CAA49675.1 P30989

Publications (2)

1
IFN-ß alters neurotrophic factor expression in T cells isolated from multiple sclerosis patients - implication of novel neurotensin/NTSR1 pathway in neuroprotection. Soltys J, Knight J, Scharf E, Pitt D, Mao-Draayer Y. American journal of translational research. 2014 6:312-9. (IHC; Human) [PubMed:24936223] [PMC:PMC4058312] Related Antibodies: LS-A938.
2
Co-localization patterns of neurotensin receptor 1 and tyrosine hydroxylase in brain regions involved in motivation and social behavior in male European starlings. Merullo DP, Spool JA, Zhao C, Riters LV. Journal of chemical neuroanatomy. 2018 April;89:1-10. [Full Text Article] [PubMed:29407461] [PMC:PMC5924578] Related Antibodies: LS-B5255.

Filtered by: None
Target
NTSR1 / NTR (44)
Reactivity
Human (41)
Mouse (13)
Rat (2)
Chimpanzee (3)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (7)
Application
IHC (26)
IHC-P (23)
WB (17)
ELISA (9)
ICC (3)
IF (7)
Peptide-ELISA (1)
Host
rabbit (43)
guinea pig (1)
Isotype
IgG (19)
Clonality
polyclonal pc (44)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (20)
Epitope
C-Terminus (9)
Cytoplasmic Domain (7)
N-Terminus (7)
aa35-84 (4)
150-230 aa, Internal (1)
His218 (1)
Internal (1)
aa181-230 (1)
aa399-418 (1)
Publications
No (42)
Yes (2)
Showing 1-25 of 44 results

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain) LS-A938
Publications (1)
Publications (1)
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
Unconjugated
50µg 0.6mg/ml  $425.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain, Biotin) LS-A109165
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain, FITC) LS-A109166
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain, AP) LS-A109163
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain, Azide-free, HRP) LS-A109167
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain, PE) LS-A109168
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (Cytoplasmic Domain, APC) LS-A109164
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (aa181-230) LS-B5255
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human NTSR1 / NTR
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-NTSR1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Western blot analysis of lysates from MCF7 cells, using NTR1 Antibody. The lane on the right is blocked with the synthesized peptide.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus) LS-A935
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus, Biotin) LS-A109117
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus, FITC) LS-A109118
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus, AP) LS-A109115
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus, APC) LS-A109116
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus, Azide-free, HRP) LS-A109119
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (N-Terminus, PE) LS-A109120
Rabbit Polyclonal to Human NTSR1 / NTR
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NTSR1 / NTR Antibody (C-Terminus) LS-A939
Rabbit Polyclonal to Human NTSR1 / NTR
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-NTSR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NTSR1 / NTR Antibody LS-C25749
Rabbit Polyclonal (IgG) to Mouse NTSR1 / NTR
Mouse
ELISA, IHC
Unconjugated
100µg 1mg/ml  $755.00

NTSR1 / NTR Antibody (150-230 aa, Internal) LS-C384984
Rabbit Polyclonal (IgG) to Human NTSR1 / NTR
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

NTSR1 / NTR Antibody (C-Terminus) LS-C25750
Rabbit Polyclonal (IgG) to Human NTSR1 / NTR
Human
ELISA, WB
Unconjugated
100µl  $725.00

NTSR1 / NTR Antibody (C-Terminus) LS-C25751
Rabbit Polyclonal (IgG) to Human NTSR1 / NTR
Human
ELISA, WB
Unconjugated
100µg  $755.00

NTSR1 / NTR Antibody (Internal) LS-C413065
Rabbit Polyclonal to Human NTSR1 / NTR
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $275.00
Immunohistochemical analysis of NTR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of NTR1 staining in SKNSH cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

NTSR1 / NTR Antibody LS-C25753
Guinea pig Polyclonal to Rat NTSR1 / NTR
Rat
ICC
Unconjugated
50µl  $445.00

NTSR1 / NTR Antibody (His218) LS-C177209
Rabbit Polyclonal to Human NTSR1 / NTR
Mouse, Human
IF, IHC, WB
Unconjugated
100µl  $345.00
Western blot of NTR1 (H218) pAb in extracts from HeLa cells.

NTSR1 / NTR Antibody (aa399-418) LS-C355705
Rabbit Polyclonal (IgG) to Human NTSR1 / NTR
Human
ICC, IF, WB
Unconjugated
100µl  $395.00
Immunofluorescence analysis of Neurotensin receptor type 1 (NTSR1) was performed using 90% confluent log phase U-87 MG cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with NTSR1 Rabbit Polyclonal Antibody at 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (H+L) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with DAPI. F-actin (Panel c: red) was stained with Rhodamine Phalloidin. Panel d represents the merged image showing membranous localization. Panel e shows the no primary antibody control. The images were captured at 60X magnification.
WB using Neurotensin receptor 1 (NTSR1) Antibody

NTSR1 / NTR Antibody LS-C806530
Rabbit Polyclonal (IgG) to Human NTSR1 / NTR
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Showing 1-25 of 44 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).