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NTN1 / Netrin 1

netrin 1

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Gene Name: netrin 1
Synonyms: NTN1, Netrin 1, Netrin 1, mouse, homolog of, Netrin-1, NTN1L
Target Sequences: NM_004822 NP_004813.2 O95631

Publications (2)

1
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities. Seiko Ikezu , Hana Yeh , Jean-Christophe Delpech , Maya E Woodbury , Alicia A Van Enoo, Zhi Ruan, Sudhir Sivakumaran, Yang You, Carl Holland, Teresa Guillamon-Vivancos, Asuka Yoshii-Kitahara, Mina B Botros, Charlotte Madore, Pin-Hao Chao, Ankita Desani, Solaiappan Manimaran, Srinidhi Venkatesan Kalavai, W Evan Johnson, Oleg Butovsky, Maria Medalla, Jennifer I Luebke, Tsuneya Ikezu. Molecular psychiatry. 2020 February; [Full Text Article] [PubMed:32071385] [PMC:PMC7431382]
2
PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling. Jiwen Li, Catharina Conrad, Tingting W Mills, Nathaniel K Berg, Boyun Kim, Wei Ruan, Jae W Lee, Xu Zhang, Xiaoyi Yuan, Holger K Eltzschig. The Journal of experimental medicine. 2021 June;218:e20210008. [Full Text Article] [PubMed:33891683] [PMC:PMC8077173] Related Antibodies: LS-C743016.

☰ Filters
Products
Proteins (6)
Recombinant (6)
NTN1 / Netrin 1 (6)
No (6)
DDK (Flag) (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-GST (1)
His-GST, N-terminus (1)
Human IgG1 Fc (1)
Human (4)
Mouse (1)
Rat (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
NTN1 / Netrin 1 Protein - Recombinant Netrin 1 (Ntn1) by SDS-PAGE
Select
Human NTN1 / Netrin 1 Protein (Recombinant His, N-Terminal) (Pro313-Pro565) - LS-G133004
E. coli
His, N-Terminal
55.5kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
NTN1 / Netrin 1 Protein - Recombinant Netrin 1 (Ntn1) by SDS-PAGE
Select
Rat NTN1 / Netrin 1 Protein (Recombinant His-GST, N-terminus) (Pro313-Pro565) - LS-G132608
E. coli
His-GST, N-terminus
58kDa
10 µg/$288; 50 µg/$487; 200 µg/$972; 100 µg/$780; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
NTN1 / Netrin 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Human NTN1 / Netrin 1 Protein (Recombinant GST, N-terminus) (aa495-604) - LS-G61118
Wheat Germ Extract
GST, N-terminus
2 µg/$439
Select
Human NTN1 / Netrin 1 Protein (Recombinant DDK (Flag)) (aa25-604) - LS-G3894
HEK 293 Cells
DDK (Flag)
Less than 0.01 EU/µg protein (determined by LAL method).
~80kDa (SDS-PAGE)
10 µg/$386
NTN1 / Netrin 1 Protein - Netrin-1 (human):Fc (human) (rec.) triggers a DCC-dependent phosphorylation of ERK1/2. Method: HEK 293 cells (Control) or HEK 293 expressing the netrin-1 receptor DCC were incubated with netrin-1 (human):Fc (human) (rec.) (5 nM) for the indicated time points (shown in minutes). Antibodies against DCC, total ERK1/2 or phospho-ERK1/2 were used and visualized with a chemiluminescence detection system. Picture courtesy of Nicolas Rama, Prof. Patrick Mehlen lab, Centre Leon Berard, Lyon
Select
Human NTN1 / Netrin 1 Protein (Recombinant Human IgG1 Fc) (aa25-604) - LS-G3911
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~90kDa (SDS-PAGE)
10 µg/$414
NTN1 / Netrin 1 Protein - Recombinant Netrin 1 By SDS-PAGE
Select
Mouse NTN1 / Netrin 1 Protein (Recombinant His-GST) (aa313-565) - LS-G14327
E. coli
His-GST
55.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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