NTHL1

nth endonuclease III-like 1 (E. coli)

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

NTHL1 (6)

Publications

No (6)

Tag

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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NTHL1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117927

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

100 µg/$494

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Human NTHL1 Protein (Recombinant His, N-Terminal) - LS-G144464

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

34.2 kDa

Price:

50 µg/$419

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Human NTHL1 Protein (Recombinant GST) (Full Length) - LS-G29554

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

60 kDa

Price:

2 µg/$439

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Human NTHL1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67388

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

20 µg/$1,107

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Human NTHL1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79719

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

20 µg/$150

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Human NTHL1 Protein (Recombinant His) - LS-G1437

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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