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Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Gene Name: | 5',3'-nucleotidase, mitochondrial |
Synonyms: | NT5M, 5(3)-deoxyribonucleotidase, 5 nucleotidase, mitochondrial, Deoxy-5-nucleotidase 2, DNT-2, MdN, Mitochondrial 5 nucleotidase, DNT2 |
Target Sequences: | NM_020201 NP_064586.1 Q9NPB1 |
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