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NSUN4

NOP2/Sun domain family, member 4

Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.

Gene Name: NOP2/Sun domain family, member 4
Synonyms: NSUN4, NOL1/NOP2/Sun domain family 4, RP4-603I14.2, SHTAP
Target Sequences: AK021577 BAB13847.1 Q96CB9

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
NSUN4 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
NSUN4 Protein - 12.5% SDS-PAGE of human NSUN4 stained with Coomassie Blue
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Wheat Germ Extract
GST
69.5 kDa
2 µg/$439
NSUN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
42.9 kDa
20 µg/$150
NSUN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.9 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).