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NSF

N-ethylmaleimide-sensitive factor

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.

Gene Name:	N-ethylmaleimide-sensitive factor
Synonyms:	NSF, NEM-sensitive fusion protein, SKD2, Vesicular-fusion protein NSF, Vesicle-fusing ATPase
Target Sequences:	NM_006178 NP_006169.2 P46459

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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