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NRXN3

neurexin 3

NRXN3 is a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

Gene Name: neurexin 3
Family/Subfamily: Neurexin , Not assigned-Other
Synonyms: NRXN3, C14orf60, KIAA0743, Neurexin III-beta, Neurexin 3, Neurexin III, Neurexin III-alpha, Neurexin-3-beta
Target Sequences: NM_004796 NP_004787.2 Q9Y4C0

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Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
NRXN3 (10)
No (10)
Fc (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (7)
Human (7)
293T Cells (3)
HEK 293 Cells (4)
Human Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
36 kDa
100 µg/$721
NRXN3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NRXN3 Protein - Purified recombinant protein NRXN3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
114.6 kDa
20 µg/$1,107
NRXN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
50.7 kDa
20 µg/$150
NRXN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
117.32 kDa
20 µg/$215
NRXN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43 kDa
20 µg/$215
NRXN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
43 kDa
100 µg/$710
NRXN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
50.7 kDa
100 µg/$494
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
61.6 kDa
100 µg/$600
NRXN3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
117.32 kDa
100 µg/$710
Viewing 1-10 of 10 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).