Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

NRSF / REST

RE1-silencing transcription factor

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.

Gene Name: RE1-silencing transcription factor
Synonyms: REST, X2 box repressor, XBR, NRSF
Target Sequences: NM_005612 NP_005603.3 Q13127

Publications (1)

1
The Rare YAP1 Subtype of SCLC Revisited in a Biobank of 39 Circulating Tumor Cell Patient Derived Explant Models: A Brief Report. Sarah M Pearsall, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kristopher K Frese, Melanie Galvin, Alastair Kerr, Mathew Carter, Lynsey Priest, Fiona Blackhall, Kathryn L Simpson, Caroline Dive. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2020 December;15:1836-1843. [Full Text Article] [PubMed:32721553] [PMC:PMC7718082] Related Antibodies: LS-C668231.

☰ Filters
Products
Antibodies (36)
Primary (36)
NRSF / REST (36)
Human (35)
Mouse (10)
Rat (10)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (6)
Pig (3)
Rabbit (3)
IHC (5)
IHC-P (4)
WB (27)
ELISA (7)
ICC (1)
IF (5)
IP (3)
Peptide-ELISA (2)
rabbit (35)
goat (1)
IgG (24)
polyclonal pc (36)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (17)
aa542-570 (7)
aa20-69 (4)
aa972-1021 (4)
aa1050-C-term (2)
C-Terminus (1)
Internal Region (1)
aa800-850 (1)
aa801-1097 (1)
No (35)
Yes (1)
NRSF / REST Antibody - Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa1050-C-term) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µl/$295; 100 µl/$514
NRSF / REST Antibody - Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human mucinous ovarian carcinoma. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:250.
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa1050-C-term) Antibody
Human
IHC, IHC-P
Unconjugated
2.5 µg/$295; 100 µl/$532
NRSF / REST Antibody - REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NRSF / REST Rabbit anti-Mouse Polyclonal (aa20-69) Antibody
Mouse
WB
Unconjugated
100 µl/$424
NRSF / REST Antibody - REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NRSF / REST Rabbit anti-Mouse Polyclonal (aa20-69) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
NRSF / REST Antibody - REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NRSF / REST Rabbit anti-Mouse Polyclonal (aa20-69) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
NRSF / REST Antibody - REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NRSF / REST Rabbit anti-Mouse Polyclonal (aa20-69) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
NRSF / REST Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IF, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$830
NRSF / REST Antibody - Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa800-850) Antibody
Human
IHC, IHC-P, IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
NRSF / REST Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$351
NRSF / REST Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using REST Polyclonal Antibody at dilution of 1:50(×200)
Select
NRSF / REST Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
NRSF / REST Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
NRSF / REST Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
NRSF / REST Antibody - Western blot analysis of REST using COLO205 whole lysates.
Select
NRSF / REST Rabbit anti-Human Polyclonal Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NRSF / REST Antibody - Immunofluorescent analysis of HepG2 cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
NRSF / REST Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
50 µg/$294; 100 µg/$360
NRSF / REST Antibody - Antibody (0.3µg/ml) staining of HEK293 (A) and HeLa (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
NRSF / REST Goat anti-Human Polyclonal (Internal Region) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa801-1097) Antibody
Mouse, Rat, Human
WB
Unconjugated
200 µg/$809
Select
NRSF / REST Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Rat, Human
WB
APC Conjugated
100 µl/$1,038
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) Antibody
Human
WB
Unconjugated
200 µl/$734
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
NRSF / REST Antibody - REST antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa972-1021) Antibody
Human
WB
Unconjugated
100 µl/$424
NRSF / REST Antibody - REST Antibody western blot of Jurkat cell line lysates (35 ug/lane). The REST antibody detected the REST protein (arrow).
Select
NRSF / REST Rabbit anti-Human Polyclonal (aa542-570) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 26-36 of 36 product results


Filtered By:
Products: Antibodies


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).