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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NRSF / REST

RE1-silencing transcription factor

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.

Gene Name: RE1-silencing transcription factor
Synonyms: REST, X2 box repressor, XBR, NRSF
Target Sequences: NM_005612 NP_005603.3 Q13127

Filtered By: None
Target
NRSF / REST (37)
Reactivity
Human (37)
Mouse (11)
Rat (11)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (6)
Guinea pig (4)
Horse (4)
Monkey (8)
Pig (4)
Rabbit (4)
Application
IHC (5)
IHC-P (5)
WB (30)
ELISA (7)
ICC (1)
IF (7)
IP (4)
Peptide-ELISA (1)
Host
rabbit (36)
goat (1)
Isotype
IgG (23)
Clonality
polyclonal pc (37)
Format
AP Conjugated (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (16)
Epitope
aa542-570 (8)
aa20-69 (4)
aa972-1021 (4)
C-Terminus (3)
aa800-850 (1)
aa801-1097 (1)
aa873-877 (1)
internal region (1)
Publications
No (37)
Showing 1-25 of 37 results

NRSF / REST Antibody IHC-plus™ LS-B15559
Rabbit Polyclonal to Human NRSF / REST
Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.

NRSF / REST Antibody (C-Terminus) LS-C90909
Rabbit Polyclonal to Human NRSF / REST
Human
IF IHC IHC-P IP WB
Unconjugated
100µg 1mg/ml  $770.00

NRSF / REST Antibody (aa542-570) LS-C324613
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
WB
Unconjugated
200µl  $530.00

NRSF / REST Antibody (aa542-570, Biotin) LS-C223856
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

NRSF / REST Antibody (aa542-570, FITC) LS-C223857
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA WB
FITC Conjugated
200µl  $680.00

NRSF / REST Antibody (aa542-570, Azide-free, HRP) LS-C223858
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA WB
HRP Conjugated, Azide-free
200µl 0.55mg/ml  $680.00

NRSF / REST Antibody (aa542-570, PE) LS-C223859
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA WB
PE Conjugated
200µl  $680.00

NRSF / REST Antibody (aa542-570, APC) LS-C223855
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA WB
APC Conjugated
200µl  $680.00

NRSF / REST Antibody (aa542-570, AP) LS-C223854
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA WB
AP Conjugated
200µl  $680.00

NRSF / REST Antibody (aa20-69) LS-C145441
Rabbit Polyclonal to Mouse NRSF / REST
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

NRSF / REST Antibody (aa20-69, HRP) LS-C437325
Rabbit Polyclonal to Mouse NRSF / REST
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

NRSF / REST Antibody (aa20-69, Biotin) LS-C437323
Rabbit Polyclonal to Mouse NRSF / REST
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

NRSF / REST Antibody (aa20-69, FITC) LS-C437324
Rabbit Polyclonal to Mouse NRSF / REST
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
REST antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

NRSF / REST Antibody (C-Terminus) LS-C287424
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
IF IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

NRSF / REST Antibody (aa800-850) LS-C287422
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
IF IHC IHC-P IP
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

NRSF / REST Antibody LS-C668231
Rabbit Polyclonal to Human NRSF / REST
Human
ICC IF WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunofluorescence Image
Western blot Image
Immunofluorescence Image
Western blot Image

NRSF / REST Antibody (C-Terminus) LS-C286412
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
IF IHC IHC-P
Unconjugated
100µl  $415.00
Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human mucinous ovarian carcinoma. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:250.
Detection of Human REST by Immunohistochemistry. Sample: FFPE section of human mucinous ovarian carcinoma. Antibody: Affinity purified rabbit anti-REST used at a dilution of 1:250.

NRSF / REST Antibody LS-C754945
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
ELISA IP WB
Unconjugated
100µg  $375.00

NRSF / REST Antibody LS-C746804
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
IF
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00

NRSF / REST Antibody LS-C675037
Rabbit Polyclonal (IgG) to Human NRSF / REST
Human
IF
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunofluorescent analysis of HepG2 cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of HepG2 cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

NRSF / REST Antibody (internal region) LS-C742385
Goat Polyclonal to Human NRSF / REST
Human
Peptide-ELISA WB
Unconjugated
100µg  $405.00
Antibody (0.3µg/ml) staining of HEK293 (A) and HeLa (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.3µg/ml) staining of HEK293 (A) and HeLa (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

NRSF / REST Antibody (aa801-1097) LS-C17676
Rabbit Polyclonal (IgG) to Human NRSF / REST
Mouse, Rat, Human
WB
Unconjugated
200µg  $635.00

NRSF / REST Antibody (aa972-1021) LS-C109670
Rabbit Polyclonal to Human NRSF / REST
Human, Monkey
WB
Unconjugated
50µg  $365.00
REST antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
REST antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NRSF / REST Antibody (aa542-570) LS-C162546
Rabbit Polyclonal to Human NRSF / REST
Human
WB
Unconjugated
400µl  $305.00
REST Antibody western blot of Jurkat cell line lysates (35 ug/lane). The REST antibody detected the REST protein (arrow).
REST Antibody western blot of Jurkat cell line lysates (35 ug/lane). The REST antibody detected the REST protein (arrow).

NRSF / REST Antibody (aa873-877) LS-C205117
Rabbit Polyclonal to Human NRSF / REST
Human
WB
Unconjugated
50µl 1mg/ml  $355.00
Western blot of extract from HeLa cells using REST antibody
Western blot of extract from HeLa cells using REST antibody
Showing 1-25 of 37 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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