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NRGN / Neurogranin

neurogranin (protein kinase C substrate, RC3)

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Gene Name: neurogranin (protein kinase C substrate, RC3)
Synonyms: NRGN, Hng, Neurogranin, Ng, Protein kinase C substrate, RC3, Calmodulin-binding protein
Target Sequences: NM_006176 NP_006167.1 Q92686

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
NRGN / Neurogranin (8)
No (8)
GST (1)
His (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
Select
E. coli
78 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
8.58 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
NRGN / Neurogranin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
7.4 kDa
100 µg/$494
NRGN / Neurogranin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
7.4 kDa
100 µg/$494
NRGN / Neurogranin Protein - 12.5% SDS-PAGE of human NRGN stained with Coomassie Blue
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Wheat Germ Extract
GST
34.32 kDa
10 µg/$479; 25 µg/$670
NRGN / Neurogranin Protein - Purified recombinant protein NRGN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
7.4 kDa
20 µg/$1,107
NRGN / Neurogranin Protein - Purified recombinant protein NRGN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
7.4 kDa
20 µg/$1,107
NRGN / Neurogranin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
7.4 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
7.4 kDa
20 µg/$150
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).