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NRG2

neuregulin 2

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.

Gene Name: neuregulin 2
Family/Subfamily: Neuregulin , not assigned-Neuregulin
Synonyms: NRG2, DON1, HRG2, Neuregulin 2, Pro-NRG2, Divergent of neuregulin-1, Don-1, NTAK
Target Sequences: NM_013982 NP_053585.1 O14511

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
NRG2 (7)
No (7)
6His, N-terminus (1)
GST, N-terminus (1)
His (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (5)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (1)
NRG2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
NRG2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NRG2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.5 kDa
20 µg/$215
NRG2 Protein - Recombinant Neuregulin 2 By SDS-PAGE
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E. coli
His
13.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
NRG2 Protein - Recombinant Neuregulin 2 By SDS-PAGE
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E. coli
His-T7
26.6 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,681
NRG2 Protein
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E. coli
His-SUMO
48.76 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
NRG2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.5 kDa
100 µg/$710
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).