NRG1 / Heregulin / Neuregulin

neuregulin 1

Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentialtion of epithelial, neuronal, glial, and other types of cells.

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Products

ELISA Kits (33)

Type

Competitive EIA (1)

Custom (2)

Development Kit (3)

Sandwich (24)

Sandwich CLIA (3)

Target

NRG1 / Heregulin / Neuregulin (33)

Reactivity

Human (14)

Mouse (5)

Rat (7)

Chicken (2)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit Core (2)

DevKit DuoPlus (1)

Format

1000 Wells (1)

12 x 8-Well Microstrips (2)

200 Wells (1)

96-Well Microplate (6)

96-Well Strip Plate (22)

Antibody Pair and Standard (1)

Publications

No (33)

Sample Type

Cell Culture Supernatants (8)

Cell Lysates (5)

Cell Supernatant (1)

Plasma (19)

Serum (19)

Tissue Homogenates (8)

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Mouse NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F5751

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F10529

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$718

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F50001

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

12.29 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$700

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F12193

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse NRG1 / Heregulin / Neuregulin (Competitive EIA) ELISA Kit - LS-F28504

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

250 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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DevKit Core Human NRG1 / Heregulin / Neuregulin ELISA Development Kit - LS-F31264

Type:

Development Kit

Format:

1000 Wells

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 405nm (ABTS)

Price:

1 Test/$540

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F31464

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$669

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F5036

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Human NRG1 / Heregulin / Neuregulin (Custom ELISA) ELISA Kit - LS-F50514

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

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Chicken NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46042

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46044

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Guinea pig NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46045

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46046

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46047

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Sheep NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46048

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

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DevKit DuoPlus Human NRG1 / Heregulin / Neuregulin ELISA Development Kit - LS-F71442

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,080; 1000 Wells/$1,577

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F74798

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F39149

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$820

Select

DevKit Core Human NRG1 / Heregulin / Neuregulin ELISA Development Kit - LS-F57480

Type:

Development Kit

Format:

200 Wells

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 405nm (ABTS)

Price:

1 Test/$180

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Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F13361

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Mouse NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F24027

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Chicken NRG1 / Heregulin / Neuregulin (Custom ELISA) ELISA Kit - LS-F18686

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

Select

Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F22647

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F27093

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F27535

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

2.5 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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