NR1I3 / CAR

nuclear receptor subfamily 1, group I, member 3

NR1I3 / CAR is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (33)

Type

Over-Expression Lysate (28)

Recombinant (5)

Target

NR1I3 / CAR (33)

Publications

No (33)

Tag

GST (1)

GST, N-terminus (1)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (28)

Species

Human (18)

Mouse (1)

Rat (1)

Source

293T Cells (15)

E. coli (3)

HEK 293 Cells (13)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human NR1I3 / CAR Protein (Recombinant GST, N-terminus) (aa2-59) - LS-G61304

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82862

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82863

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82864

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.7 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82866

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82867

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.8 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82869

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.5 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82872

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.1 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82873

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.1 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82876

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.6 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82878

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.1 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82883

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.3 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82884

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.3 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82885

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82880

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.2 kDa

Price:

20 µg/$150

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Human NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82882

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

20 µg/$150

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Mouse NR1I3 / CAR Protein (Recombinant His-T7) (aa1-247) - LS-G24849

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.8 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Rat NR1I3 / CAR Protein (Recombinant His-T7) (aa1-247) - LS-G24850

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.8 kDa

Price:

10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

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Human NR1I3 / CAR Protein (Recombinant His-SUMO) (Full Length) - LS-G21688

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

55.7 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human NR1I3 / CAR Protein (Recombinant GST) (Full Length) - LS-G31878

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.3 kDa

Price:

2 µg/$439

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NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116174

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

100 µg/$494

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NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119996

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

100 µg/$494

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NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119997

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

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NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119999

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.7 kDa

Price:

100 µg/$494

Select

NR1I3 / CAR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119998

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.5 kDa

Price:

100 µg/$494

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