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NR1H2 / LXR Beta

nuclear receptor subfamily 1, group H, member 2

Liver X receptor beta (LXR beta), a NR1 thyroid hormone-like receptor, has been shown to affect cholesterol and bile acid metabolism, as well as fatty acid metabolism. LXR beta mediates gene products controlling intracellular cholesterol homeostasis through the interaction with oxysterols including 22(R)-hydroxycholesterol, 24(S)-hydroxycholesterol, and 24(S),25-epoxycholesterol. LXR beta binds as a heterodimer to target sequences with retinoid X receptors and has been shown to activate a diverse set of genes involved in cholesterol and fatty acid metabolism, including ABCA1, ABCG5, ABCG8, SREBP-1c, fatty acid synthase (FAS), and the apoE/C-I/C-IV/C-II gene cluster upon ligand activation. Recently both LXR alpha and LXR beta have been shown to be important factors in atherosclerosis (Tangirala et al. 2002)

Gene Name: nuclear receptor subfamily 1, group H, member 2
Family/Subfamily: NHR , NR1 Thyroid hormone-like
Synonyms: NR1H2, Liver X receptor beta, LXR beta, LXR-b, LXRB, Lxrbeta, NER, Nuclear receptor NER, LX receptor beta, Ubiquitous receptor, RIP15, Liver X nuclear receptor beta, NER-I, Oxysterols receptor LXR-beta, UNR
Target Sequences: NM_007121 NP_009052.3 P55055

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Products
Antibodies (48)
Primary (48)
NR1H2 / LXR Beta (48)
Human (36)
Mouse (23)
Rat (13)
Bat (6)
Bovine (6)
Chimpanzee (12)
Dog (9)
Gibbon (9)
Guinea pig (15)
Hamster (6)
Horse (6)
Monkey (6)
Orangutan (3)
Pig (7)
Rabbit (12)
Xenopus (3)
IHC (3)
IHC-P (3)
WB (42)
ELISA (14)
ICC (1)
IF (3)
Peptide-ELISA (2)
rabbit (46)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
IgG (22)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (47)
2H2-H3 (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (8)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (2)
Unconjugated (18)
N-Terminus (12)
aa26-53 (7)
aa227-276 (4)
aa323-372 (4)
aa2-15 (1)
No (48)
NR1H2 / LXR Beta Antibody - Anti-NR1H2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
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NR1H2 / LXR Beta Goat anti-Human Polyclonal (aa2-15) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
NR1H2 / LXR Beta Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NR1H2 / LXR Beta Antibody - Western Blot; Sample: Recombinant protein.
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NR1H2 / LXR Beta Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
NR1H2 / LXR Beta Antibody - Western Blot; Sample: Recombinant protein.
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NR1H2 / LXR Beta Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
NR1H2 / LXR Beta Antibody - Western Blot; Sample: Recombinant protein.
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NR1H2 / LXR Beta Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
NR1H2 / LXR Beta Antibody - Western Blot; Sample: Recombinant protein.
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NR1H2 / LXR Beta Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
NR1H2 / LXR Beta Antibody - Western Blot; Sample: Recombinant protein.
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NR1H2 / LXR Beta Rabbit anti-Mouse Polyclonal (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
NR1H2 / LXR Beta Antibody - Immunohistochemistry of paraffin-embedded human melanoma cancer at dilution of 1:100
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
NR1H2 / LXR Beta Antibody - Immunofluorescence of paraformaldehyde-fixed HeLa, using LXR beta antibody at 1:200 dilution.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$450
NR1H2 / LXR Beta Antibody - NR1H2 monoclonal antibody (M01), clone 2H2-H3 Western Blot analysis of NR1H2 expression in LNCaP.
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NR1H2 / LXR Beta Mouse anti-Human Monoclonal (2H2-H3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
NR1H2 / LXR Beta Antibody - Western blot of LXR-B in human lung tissue lysate with LXR-B antibody at (A) 1 and (B) 2 ug/ml.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$460
NR1H2 / LXR Beta Antibody - Transfected 293T Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
NR1H2 / LXR Beta Antibody - Sample (30 ug of whole cell lysate). A: A549 10% SDS PAGE. NR1H2 antibody diluted at 1:1000.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$450
NR1H2 / LXR Beta Antibody - NR1H2 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa323-372) Antibody
Human
WB
Unconjugated
100 µl/$424
NR1H2 / LXR Beta Antibody - NR1H2 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
NR1H2 / LXR Beta Antibody - HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa227-276) Antibody
Human
WB
Unconjugated
100 µl/$397
NR1H2 / LXR Beta Antibody - Western blot of lysate from HepG2 cell line, using NR1H2 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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NR1H2 / LXR Beta Rabbit anti-Human Polyclonal (aa26-53) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 48 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).