NPRB / NPR2

natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)

NPRB / NPR2 is natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

NPRB / NPR2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His-SUMO (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human NPRB / NPR2 Protein (Recombinant GST) (Full Length) - LS-G29540

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

140.5 kDa

Price:

2 µg/$439

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Human NPRB / NPR2 Protein (Recombinant GST, N-terminus) (aa131-230) - LS-G59439

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NPRB / NPR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74671

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.02 kDa

Price:

20 µg/$215

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Human NPRB / NPR2 Protein (Recombinant His-SUMO) (aa23-458) - LS-G21015

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

64.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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NPRB / NPR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116919

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.02 kDa

Price:

100 µg/$710

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