NPRA / NPR1

natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).

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Products

ELISA Kits (8)

Type

Competitive EIA (1)

Custom (2)

Sandwich (5)

Target

NPRA / NPR1 (8)

Reactivity

Human (3)

Mouse (2)

Rat (3)

Format

96-Well Strip Plate (8)

Publications

No (8)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (2)

Plasma (4)

Serum (4)

Tissue Homogenates (5)

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Human NPRA / NPR1 (Sandwich ELISA) ELISA Kit - LS-F10832

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat NPRA / NPR1 (Custom ELISA) ELISA Kit - LS-F19320

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse NPRA / NPR1 (Custom ELISA) ELISA Kit - LS-F19319

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse NPRA / NPR1 (Competitive EIA) ELISA Kit - LS-F38882

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

12.35 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Human NPRA / NPR1 (Sandwich ELISA) ELISA Kit - LS-F32694

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat NPRA / NPR1 (Sandwich ELISA) ELISA Kit - LS-F32695

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

3.12 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat NPRA / NPR1 (Sandwich ELISA) ELISA Kit - LS-F8725

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$893

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Human NPRA / NPR1 (Sandwich ELISA) ELISA Kit - LS-F7398

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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