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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NPRA / NPR1

natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).

Gene Name: natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
Family/Subfamily: Protein Kinase , Receptor guanylate cyclase
Synonyms: NPR1, ANPR-A, ANPa, Guanylate cyclase A, GUCY2A, GC-A, GUC2A, Natriuretic peptide receptor A, NPRA, Natriuretic peptide receptor 1, NPPA receptor, ANP-A, ANPRA, NPR-A
Target Sequences: NM_000906 NP_000897.3 P16066

Filtered by: None
Target
NPRA / NPR1 (33)
Reactivity
Human (24)
Mouse (22)
Rat (13)
Application
IHC (23)
IHC-Fr (1)
IHC-P (4)
WB (23)
ELISA (26)
ICC (7)
IF (8)
Host
rabbit (28)
mouse (3)
goat (1)
rat (1)
Isotype
IgG (23)
IgG1 (3)
IgG2a (1)
Clonality
monoclonal mc (4)
polyclonal pc (29)
Clone
OTI7H7 (2)
Format
AP Conjugated (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (3)
Carrier-free (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (18)
Epitope
aa198-226 (8)
N-Terminus (7)
aa33-473 (5)
aa29-469 (2)
aa294-308 (2)
aa746-1006 (2)
Publications
No (32)
Yes (1)
Showing 1-25 of 33 results

IHC-plus™ NPRA / NPR1 Antibody LS-B15586
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of extracts of various cell lines, using NPR1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 40s.

NPRA / NPR1 Antibody LS-C109432
Publications (1)
Publications (1)
Rabbit Polyclonal to Human NPRA / NPR1
Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 0.5mg/ml  $355.00
Immunofluorescence of paraformaldehyde-fixed HeLa, using NPR-A antibody at 1:200 dilution.
Sample (30 ug of whole cell lysate). A: H1299. B: Raji. 7.5% SDS PAGE. NPR1 antibody diluted at 1:3000

NPRA / NPR1 Antibody (aa29-469) LS-C124222
Rat Monoclonal (IgG2a) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, IHC-Fr
Unconjugated
100µg  $650.00

NPRA / NPR1 Antibody (aa33-473) LS-C73160
Mouse Monoclonal (IgG1) to Human NPRA / NPR1
Human
ELISA, WB
Unconjugated
100µg  $650.00

NPRA / NPR1 Antibody (aa294-308) LS-C37436
Rabbit Polyclonal to Human NPRA / NPR1
Human
IHC, IHC-P, WB
Unconjugated
20µl  $425.00

NPRA / NPR1 Antibody (aa198-226) LS-C164506
Rabbit Polyclonal to Mouse NPRA / NPR1
Mouse, Human
IHC, WB
Unconjugated
400µl  $325.00
Mouse Npr1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded mouse duodenum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Mouse Npr1 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The Npr1 antibody detected the Npr1 protein (arrow).

NPRA / NPR1 Antibody (aa294-308) LS-C122196
Rabbit Polyclonal to Human NPRA / NPR1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
20µl  $415.00; 100µl  $815.00

NPRA / NPR1 Antibody (N-Terminus) LS-C323242
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
200µl  $590.00

NPRA / NPR1 Antibody (N-Terminus, Biotin) LS-C264030
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, ICC, IF, IHC
Biotin Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (N-Terminus, FITC) LS-C264031
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, ICC, IF, IHC
FITC Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (N-Terminus, AP) LS-C264028
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, ICC, IF, IHC
AP Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (N-Terminus, APC) LS-C264029
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, ICC, IF, IHC
APC Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (N-Terminus, Azide-free, HRP) LS-C264032
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, ICC, IF, IHC
HRP Conjugated, Azide-free
200µl  $740.00

NPRA / NPR1 Antibody (N-Terminus, PE) LS-C264035
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, ICC, IF, IHC
PE Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (aa198-226) LS-C329904
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
Unconjugated
200µl  $590.00

NPRA / NPR1 Antibody (aa198-226, Biotin) LS-C264631
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (aa198-226, FITC) LS-C264632
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (aa198-226, AP) LS-C264629
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (aa198-226, APC) LS-C264630
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

NPRA / NPR1 Antibody (aa198-226, Azide-free, HRP) LS-C264633
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

NPRA / NPR1 Antibody (aa198-226, PE) LS-C264634
Rabbit Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

NPRA / NPR1 Antibody LS-C802392
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

NPRA / NPR1 Antibody LS-C402142
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human liver cancer using NPR1 Polyclonal Antibody at dilution of 1:40.

NPRA / NPR1 Antibody LS-C405448
Rabbit Polyclonal (IgG) to Human NPRA / NPR1
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl 0.6mg/ml  $205.00; 60µl 0.6mg/ml  $235.00; 120µl 0.6mg/ml  $295.00; 200µl 0.6mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human gastric cancer using NPR1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded Human gastric cancer using NPR1 Polyclonal Antibody at dilution of 1:30.

NPRA / NPR1 Antibody (aa29-469) LS-C37437
Goat Polyclonal (IgG) to Mouse NPRA / NPR1
Mouse
ELISA, WB
Unconjugated
100µg  $725.00
Showing 1-25 of 33 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).