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NPL / C112

N-acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase)

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.

Gene Name: N-acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase)
Synonyms: NPL, C1orf13, Sialic acid lyase, Sialate-pyruvate lyase, N-acetylneuraminate lyase, NAL, Sialate lyase, Sialic acid aldolase, C112, DHDPS1, NALase, NPL1
Target Sequences: NM_030769 NP_110396.1 Q9BXD5

☰ Filters
Antibodies (19)
Proteins (5)
Over-Expression Lysate (2)
Primary (19)
Recombinant (3)
NPL / C112 (24)
Human (17)
Mouse (3)
Rat (5)
Chimpanzee (3)
Dog (3)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
WB (16)
ELISA (11)
IF (3)
rabbit (19)
IgG (14)
polyclonal pc (19)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
aa49-77 (7)
aa61-110 (4)
aa1-237 (1)
No (24)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
NPL / C112 Antibody - Immunofluorescent analysis of Hela cells using CSB-PA874803LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
NPL / C112 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
NPL / C112 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
NPL / C112 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
NPL / C112 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
NPL / C112 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$331
Select
NPL / C112 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
NPL / C112 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa1-237) Antibody
Human
WB
Unconjugated
100 µl/$408
NPL / C112 Antibody - NPL antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa61-110) Antibody
Human
WB
Unconjugated
100 µl/$424
NPL / C112 Antibody - NPL antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa61-110) (HRP) Antibody
Dog, Rat, Pig, Horse, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
NPL / C112 Antibody - NPL antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa61-110) (Biotin) Antibody
Dog, Rat, Pig, Horse, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
NPL / C112 Antibody - NPL antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa61-110) (FITC) Antibody
Dog, Rat, Pig, Horse, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
NPL / C112 Antibody - NPL Antibody western blot of U251 cell line lysates (35 ug/lane). The NPL antibody detected the NPL protein (arrow).
Select
NPL / C112 Rabbit anti-Human Polyclonal (aa49-77) Antibody
Human
WB
Unconjugated
400 µl/$393
NPL / C112 Protein - 12.5% SDS-PAGE of human NPL stained with Coomassie Blue
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Wheat Germ Extract
GST
53.2 kDa
10 µg/$479; 25 µg/$670
NPL / C112 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35 kDa
20 µg/$150
NPL / C112 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
35 kDa
100 µg/$494
NPL / C112 Protein - Purified recombinant protein NPL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
35 kDa
20 µg/$1,107
NPL / C112 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-24 of 24 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).