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NOVA1

neuro-oncological ventral antigen 1

NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

Gene Name: neuro-oncological ventral antigen 1
Synonyms: NOVA1, Nova-1, Onconeural ventral antigen 1, RNA-binding protein Nova-1, Paraneoplastic Ri antigen
Target Sequences: NM_002515 NP_002506.2 P51513

Publications (3)

1
Dynamic expression pattern of neuro-oncological ventral antigen 1 (Nova1) in the rat brain after focal cerebral ischemia/reperfusion insults. Li H, Sun C, Wang Y, Gao Y, Liu Y, Gao Y, Li X, Zhang C. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2013 61:45-54. (WB, IHC-P; Rat) [Full Text Article] [PubMed:23042482] [PMC:PMC3534313]
2
High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma. Zhang YA, Zhu JM, Yin J, Tang WQ, Guo YM, Shen XZ, Liu TT. PloS one. 2014 9:e90955. (WB; Human) [Full Text Article] [PubMed:24608171] [PMC:PMC3946567] Related Antibodies: LS-B3259.
3
RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-?2. Zhang YA, Liu HN, Zhu JM, Zhang DY, Shen XZ, Liu TT. Journal of biomedical science. 2016 23:71. (WB; Human) [Full Text Article] [PubMed:27733149] [PMC:PMC5062898] Related Antibodies: LS-B3259.

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (6)
Recombinant (8)
NOVA1 (14)
No (14)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (8)
Human (11)
293T Cells (3)
E. coli (2)
HEK 293 Cells (6)
Wheat Germ Extract (3)
Purified (4)
Low endotoxin level (1)
NOVA1 Protein - Recombinant Neuro Oncological Ventral Antigen 1 (NOVA1) by SDS-PAGE
Select
E. coli
His-T7, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.8kDa
10 µg/$262; 50 µg/$370; 200 µg/$736; 100 µg/$591; 1 mg/$1,701; 500 µg/$1,274; 5 mg/$3,620
NOVA1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$469; 25 µg/$630
NOVA1 Protein - Purified recombinant protein NOVA1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$1,024
NOVA1 Protein - Purified recombinant protein NOVA1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
49.1 kDa
20 µg/$1,005
NOVA1 Protein
Select
E. coli
6His, N-terminus
56 kDa
10 µg/$255; 100 µg/$355; 50 µg/$305
NOVA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49.1 kDa
100 µg/$607
NOVA1 Protein - 12.5% SDS-PAGE of human NOVA1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
78.1 kDa
2 µg/$429
NOVA1 Protein - 12.5% SDS-PAGE of human NOVA1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
81.29 kDa
10 µg/$469; 25 µg/$630
NOVA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49.1 kDa
100 µg/$412
NOVA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
100 µg/$458
NOVA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$130
Select
293T Cells
Myc-DDK (Flag)
49.1 kDa
20 µg/$110
NOVA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
49.1 kDa
20 µg/$200
NOVA1 Protein
Select
HEK 293 Cells
His, N-Terminal
52 kDa (55-75 kDa reducing conditions)
10 µg/$279; 200 µg/$607; 50 µg/$350
Viewing 1-14 of 14 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).