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Nor-1 / NR4A3

nuclear receptor subfamily 4, group A, member 3

Nor-1 / NR4A3 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: nuclear receptor subfamily 4, group A, member 3
Family/Subfamily: NHR , NR4 Nerve growth factor-like
Synonyms: NR4A3, CHN, MINOR, NOR1, Neuron-derived orphan receptor, Nuclear hormone receptor NOR-1, Nor-1, CSMF, Orphan receptor nor1, TEC receptor
Target Sequences: NM_006981 NP_008912.2 Q92570

Publications (1)

1
Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy. Tomoya Kon, Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Masahiko Tomiyama, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi. Neuropathology : official journal of the Japanese Society of Neuropathology. 2015 December;35:503-9. [Full Text Article] [PubMed:26096603] Related Antibodies: LS-A2341.

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Proteins (9)
Over-Expression Lysate (6)
Recombinant (3)
Nor-1 / NR4A3 (9)
No (9)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (7)
Human (5)
Rat (1)
293T Cells (3)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Nor-1 / NR4A3 Protein - Purified recombinant protein NR4A3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
69.3 kDa
20 µg/$1,107
Nor-1 / NR4A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68 kDa
100 µg/$494
Nor-1 / NR4A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68 kDa
100 µg/$710
Nor-1 / NR4A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68 kDa
100 µg/$710
Nor-1 / NR4A3 Protein - Recombinant Neuron Derived Orphan Receptor 1 By SDS-PAGE
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E. coli
His-T7
16.9 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
Nor-1 / NR4A3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Nor-1 / NR4A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
68 kDa
20 µg/$215
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293T Cells
Myc-DDK (Flag)
68 kDa
20 µg/$150
Nor-1 / NR4A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
68 kDa
20 µg/$215
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).