NOD1

nucleotide-binding oligomerization domain containing 1

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.

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Products

ELISA Kits (2)

Type

Competitive EIA (1)

Custom (1)

Target

NOD1 (2)

Reactivity

Human (1)

Mouse (1)

Format

96-Well Strip Plate (2)

Publications

No (2)

Sample Type

Plasma (1)

Serum (1)

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Human NOD1 (Custom ELISA) ELISA Kit - LS-F49338

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse NOD1 (Competitive EIA) ELISA Kit - LS-F66474

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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