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NMRAL1 / HSCARG

NmrA-like family domain containing 1

Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP+ levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP+. Binding to NADPH is necessary to form a stable dimer.

Gene Name: NmrA-like family domain containing 1
Synonyms: NMRAL1, SDR48A1, HSCARG
Target Sequences: NM_020677 NP_065728.1 Q9HBL8

☰ Filters
Antibodies (15)
Proteins (5)
Over-Expression Lysate (2)
Primary (15)
Recombinant (3)
NMRAL1 / HSCARG (20)
Human (11)
Mouse (5)
Rat (7)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Monkey (3)
Pig (3)
IHC (1)
WB (15)
ELISA (5)
Peptide-ELISA (1)
rabbit (15)
IgG (11)
polyclonal pc (15)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (6)
N-Terminus (4)
aa216-265 (4)
No (20)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
NMRAL1 / HSCARG Antibody - Immunofluorescence staining of PC-3 cells with NMRAL1 Antibody at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
NMRAL1 / HSCARG Antibody - Western blot analysis of extracts of HeLa cells using NMRAL1 antibody. The lane on the left was treated with blocking peptide.
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Mouse Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Rat, Pig
WB
HRP Conjugated
100 µl/$469
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Mouse Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Rat, Pig
WB
Biotin Conjugated
100 µl/$469
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Mouse Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Rat, Pig
WB
FITC Conjugated
100 µl/$469
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (aa216-265) Antibody
Human
WB
Unconjugated
100 µl/$424
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (aa216-265) (HRP) Antibody
Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (aa216-265) (Biotin) Antibody
Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
NMRAL1 / HSCARG Antibody - NMRAL1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal (aa216-265) (FITC) Antibody
Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
NMRAL1 / HSCARG Antibody - Anti-NMRAL1 rabbit polyclonal antibody at 1:500 dilution. Lane A: Hela Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 33 kDa.
Select
NMRAL1 / HSCARG Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
NMRAL1 / HSCARG Protein - Purified recombinant protein NMRAL1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
33.2 kDa
20 µg/$1,107
NMRAL1 / HSCARG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
33.2 kDa
20 µg/$150
NMRAL1 / HSCARG Protein - 12.5% SDS-PAGE of human NMRAL1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
59.7 kDa
10 µg/$479; 25 µg/$670
NMRAL1 / HSCARG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
33.2 kDa
100 µg/$494
NMRAL1 / HSCARG Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-20 of 20 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).