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NME2

NME/NM23 nucleoside diphosphate kinase 2

Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.

Gene Name: NME/NM23 nucleoside diphosphate kinase 2
Synonyms: NME2, Histidine protein kinase NDKB, NDKB, NM23-H2, PUF, NDP kinase B, NDPK-B, C-myc transcription factor, NDK B, NDPKB, NM23, NM23B
Target Sequences: NM_002512 NP_002503.1 P22392

Publications (1)

1
Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model. Chu EY, Tamasas B, Fong H, Foster BL, LaCourse MR, Tran AB, Martin JF, Schutte BC, Somerman MJ, Cox TC. Journal of dental research. 2016 October;95:1265-73. (Human) [Full Text Article] [PubMed:27369589] [PMC:PMC5076757] Related Antibodies: LS-B9880.

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (8)
Recombinant (10)
NME2 (18)
No (18)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His, N-Terminal (2)
Myc-DDK (Flag) (9)
Human (13)
Mouse (1)
293T Cells (4)
E. coli (7)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (2)
NME2 Protein - Recombinant Non Metastatic Cells 2, Protein NM23B Expressed In By SDS-PAGE
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E. coli
His, N-Terminal
20.0 kDa
10 µg/$286; 50 µg/$472; 100 µg/$757; 200 µg/$945; 1 mg/$2,073; 500 µg/$1,604; 5 mg/$3,305; 2 mg/$2,262
NME2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NME2 Protein - Purified recombinant protein NME2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$1,107
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$150
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$150
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$150
Select
E. coli
None
17.2 kDa
5 µg/$246
NME2 Protein - 12.5% SDS-PAGE of human NME2 stained with Coomassie Blue
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Wheat Germ Extract
GST
42.46 kDa
10 µg/$479; 25 µg/$670
NME2 Protein
Select
E. coli
6His, N-terminus
19.4 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
NME2 Protein
Select
E. coli
His, N-Terminal
17.1 kDa
50 µg/$419
NME2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
24.2 kDa
1 mg/$1,486; 100 µg/$451; 20 µg/$339
NME2 Protein
Select
E. coli
GST, N-terminus + His, C-terminus
45.1 kDa
50 µg/$419
NME2 Protein
Select
E. coli
None
100 µg/$342; 500 µg/$641; 20 µg/$254
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
100 µg/$494
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
100 µg/$494
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
100 µg/$494
NME2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
100 µg/$494
Viewing 1-18 of 18 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).