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Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.
Gene Name: | NME/NM23 nucleoside diphosphate kinase 2 |
Synonyms: | NME2, Histidine protein kinase NDKB, NDKB, NM23-H2, PUF, NDP kinase B, NDPK-B, C-myc transcription factor, NDK B, NDPKB, NM23, NM23B |
Target Sequences: | NM_002512 NP_002503.1 P22392 |
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