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NME2

NME/NM23 nucleoside diphosphate kinase 2

Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.

Gene Name: NME/NM23 nucleoside diphosphate kinase 2
Synonyms: NME2, Histidine protein kinase NDKB, NDKB, NM23-H2, PUF, NDP kinase B, NDPK-B, C-myc transcription factor, NDK B, NDPKB, NM23, NM23B
Target Sequences: NM_002512 NP_002503.1 P22392

Publications (1)

1
Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model. Chu EY, Tamasas B, Fong H, Foster BL, LaCourse MR, Tran AB, Martin JF, Schutte BC, Somerman MJ, Cox TC. Journal of dental research. 2016 October;95:1265-73. (Human) [Full Text Article] [PubMed:27369589] [PMC:PMC5076757] Related Antibodies: LS-B9880.

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Products
Antibodies (31)
Primary (31)
NME2 (31)
Human (23)
Mouse (24)
Rat (9)
Dog (1)
Monkey (1)
Pig (1)
Rabbit (1)
IHC (16)
IHC-P (4)
WB (31)
ELISA (13)
ICC (2)
IF (5)
Peptide-ELISA (2)
rabbit (26)
mouse (5)
Product Group
IHCPlus (1)
IgG (14)
IgG1 (3)
IgG1,k (1)
IgG3,k (1)
monoclonal mc (5)
polyclonal pc (26)
1D3 (1)
4G7A8 (1)
AT2E3 (1)
OTI2F9 (2)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (19)
aa8-149 (8)
aa25-54 (7)
60-140 aa, Internal (1)
His118 (1)
Internal (1)
aa137-152 (1)
aa91-140 (1)
No (30)
Yes (1)
NME2 Antibody - Anti-NME2 / NM23 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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NME2 Rabbit anti-Human Polyclonal (aa91-140) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
NME2 Antibody - NME2 / NM23 antibody. IHC(P): Human Intestinal Cancer Tissue.
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NME2 Rabbit anti-Human Polyclonal (aa137-152) Antibody
Rabbit, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
NME2 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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NME2 Rabbit anti-Human Polyclonal (aa25-54) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NME2 Antibody - Immunoperoxidase of monoclonal antibody to NME2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]
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NME2 Mouse anti-Human Monoclonal (1D3) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
NME2 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue.
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NME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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NME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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NME2 Mouse anti-Human Monoclonal (4G7A8) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$459
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NME2 Rabbit anti-Human Polyclonal (aa25-54) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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NME2 Rabbit anti-Human Polyclonal (aa25-54) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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NME2 Rabbit anti-Human Polyclonal (aa25-54) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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NME2 Rabbit anti-Human Polyclonal (aa25-54) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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NME2 Rabbit anti-Human Polyclonal (aa25-54) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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NME2 Rabbit anti-Human Polyclonal (aa25-54) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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NME2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
NME2 Antibody - ICC/IF analysis of NME2 in HeLa cells. The cell was stained with NME2 antibody (1:100).The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
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NME2 Mouse anti-Human Monoclonal (AT2E3) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
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NME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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NME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
NME2 Antibody - Staining K562 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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NME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NME2 Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NME2 Antibody - Western blot of recombinant NME2 / NM23.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NME2 Rabbit anti-Mouse Polyclonal (aa8-149) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
NME2 Antibody - Western blot of recombinant NME2 / NM23.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NME2 Rabbit anti-Mouse Polyclonal (aa8-149) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
NME2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NME2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NME2.
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NME2 Mouse anti-Human Monoclonal (OTI2F9) Antibody
Human
WB
Unconjugated
100 µl/$434
NME2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NME2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NME2.
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NME2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F9) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
NME2 Antibody - Western blot of NM23/NDP Kinase B (H118) pAb in extracts from K562 cells.
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NME2 Rabbit anti-Human Polyclonal (His118) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
NME2 Antibody - Western blot analysis of nm23-H2 expression in MCF7 (A); HeLa (B); A431 (C); Jurkat (D); K562 (E); BJAB (F) whole cell lysates.
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NME2 Rabbit anti-Human Polyclonal (Internal) Antibody
Dog, Pig, Human
WB
Unconjugated
100 µl/$299
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).