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NME1 / NM23
NME/NM23 nucleoside diphosphate kinase 1
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
| Gene Name: | NME/NM23 nucleoside diphosphate kinase 1 |
| Synonyms: | NME1, AWD, NDKA, NB, NDK A, NM23-H1, NDP kinase A, NDPK-A, NDPKA, GAAD, Granzyme A-activated DNase, NBS, NM23 |
| Target Sequences: | NM_000269 NP_000260.1 P15531 |
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(4)
NME1 / NM23 Mouse anti-Human Monoclonal (1D7) Antibody
Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
NME1 / NM23 Rabbit anti-Mouse Polyclonal (aa6-147) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
NME1 / NM23 Mouse anti-Human Monoclonal (4B2) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
NME1 / NM23 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
NME1 / NM23 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
NME1 / NM23 Mouse anti-Human Monoclonal (4B2) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
NME1 / NM23 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
NME1 / NM23 Rabbit anti-Human Polyclonal (aa29-57) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
NME1 / NM23 Rabbit anti-Human Polyclonal (aa29-57) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
NME1 / NM23 Mouse anti-Human Monoclonal (UMAB92) Antibody
Dog, Rat, Human
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
NME1 / NM23 Mouse anti-Human Monoclonal (Carrier-free) (UMAB92) Antibody
Dog, Rat, Human
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
NME1 / NM23 Mouse anti-Human Monoclonal (UMAB91) Antibody
Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
NME1 / NM23 Mouse anti-Human Monoclonal (Carrier-free) (UMAB91) Antibody
Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
NME1 / NM23 Mouse anti-Human Monoclonal (UMAB93) Antibody
Dog, Rat, Human
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
NME1 / NM23 Mouse anti-Human Monoclonal (Carrier-free) (UMAB93) Antibody
Dog, Rat, Human
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
NME1 / NM23 Mouse anti-Human Monoclonal (UMAB94) Antibody
Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
NME1 / NM23 Mouse anti-Human Monoclonal (Carrier-free) (UMAB94) Antibody
Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
NME1 / NM23 Rabbit anti-Human Polyclonal (aa3-52) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
NME1 / NM23 Rabbit anti-Human Polyclonal (aa137-152) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
NME1 / NM23 Rabbit anti-Human Polyclonal (aa25-54) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NME1 / NM23 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
NME1 / NM23 Rabbit anti-Human Monoclonal (Preservative Free) (084) Antibody
Human
IHC-P
Unconjugated, Preservative Free
100 µl/$412
NME1 / NM23 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
100 µl/$412
NME1 / NM23 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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