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NLRP14 / NALP14
NLR family, pyrin domain containing 14
NLRP14 / NALP14 belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.
| Gene Name: | NLR family, pyrin domain containing 14 |
| Synonyms: | NLRP14, CLR11.2, GC-LRR, NOD5, PAN8, Nalp-iota, NALP14 |
| Target Sequences: | NP_789792.1 Q86W24 |
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