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NKAP
NFKB activating protein
NKAP is a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
| Gene Name: | NFKB activating protein |
| Synonyms: | NKAP, NF-kappaB activating protein, NFKB activating protein, NF-kappa-B-activating protein |
| Target Sequences: | NM_024528 NP_078804.2 Q8N5F7 |
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