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NINL

ninein-like

Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis.

Gene Name:	ninein-like
Synonyms:	NINL, KIAA0980, NLP, Ninein-like, Ninein-like protein, DJ691N24.1
Target Sequences:	NM_025176 NP_079452.3 Q9Y2I6

Publications (2)

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking. Bachmann-Gagescu R, Dona M, Hetterschijt L, Tonnaer E, Peters T, de Vrieze E, Mans DA, van Beersum SE, Phelps IG, Arts HH, Keunen JE, Ueffing M, Roepman R, Boldt K, Doherty D, Moens CB, Neuhauss SC, Kremer H, van Wijk E. PLoS genetics. 2015 11:e1005575. (WB; Human) [Full Text Article] [PubMed:26485645] [PMC:PMC4617701]

NINL and DZANK1 Co-function in Vesicle Transport and Are Essential for Photoreceptor Development in Zebrafish. Dona M, Bachmann-Gagescu R, Texier Y, Toedt G, Hetterschijt L, Tonnaer EL, Peters TA, van Beersum SE, Bergboer JG, Horn N, de Vrieze E, Slijkerman RW, van Reeuwijk J, Flik G, Keunen JE, Ueffing M, Gibson TJ, Roepman R, Boldt K, Kremer H, van Wijk E. PLoS genetics. 2015 11:e1005574. (WB; Human) [Full Text Article] [PubMed:26485514] [PMC:PMC4617706]

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