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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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NFKBIZ / IKBZ

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis.

Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Synonyms: NFKBIZ, IkB-zeta, IkappaBzeta, IKBZ, MAIL, I-kappa-B-zeta, Ikappa B-zeta variant 3, IkappaB-zeta, INAP, NF-kappa-B inhibitor zeta
Target Sequences: NM_031419 NP_113607.1 Q9BYH8

Viewing 1-25 of 31 items
NFKBIZ / IKBZ Antibody
Select
Rabbit Polyclonal to Human NFKBIZ / IKBZ
Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $265.00
NFKBIZ / IKBZ Antibody - NFKBIZ antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
NFKBIZ / IKBZ Antibody - NFKBIZ antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
NFKBIZ / IKBZ Antibody - NFKBIZ antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
NFKBIZ / IKBZ Antibody - NFKBIZ antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Mouse NFKBIZ / IKBZ
Mouse
ELISA, WB
Unconjugated
100µg   $485.00
NFKBIZ / IKBZ Antibody - Western blot of IkappaB Zeta using antibody at3 ug/ml in mouse RAW cell lysate.
Select
Rabbit Polyclonal (IgG) to Mouse NFKBIZ / IKBZ
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µg   200µl   0.5mg/ml   $335.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $545.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
HRP Conjugated
200µl   0.5mg/ml   $345.00; 500µl   0.5mg/ml   $560.00; 1ml   0.5mg/ml   $695.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
Biotin Conjugated
200µl   0.5mg/ml   $315.00; 500µl   0.5mg/ml   $475.00; 1ml   0.5mg/ml   $590.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
FITC Conjugated
200µl   0.5mg/ml   $365.00; 500µl   0.5mg/ml   $605.00; 1ml   0.5mg/ml   $755.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
APC Conjugated
200µl   0.1mg/ml   $375.00; 500µl   0.1mg/ml   $650.00; 1ml   0.1mg/ml   $815.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
PE Conjugated
200µl   0.1mg/ml   $485.00; 500µl   0.1mg/ml   $965.00; 1ml   0.1mg/ml   $1,215.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
Cy3 Conjugated
200µl   0.1mg/ml   $445.00; 500µl   0.1mg/ml   $860.00; 1ml   0.1mg/ml   $1,080.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse NFKBIZ / IKBZ
Mouse
WB
APC, Cy7 Conjugated
1ml   0.1mg/ml   $1,215.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human NFKBIZ / IKBZ
Human
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $530.00
NFKBIZ / IKBZ Antibody - Western blot of recombinant NFKBIZ / IKBZ.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human NFKBIZ / IKBZ
Human
WB
HRP Conjugated
200µl   0.5mg/ml   $345.00; 500µl   0.5mg/ml   $545.00; 1ml   0.5mg/ml   $680.00
NFKBIZ / IKBZ Antibody - 1:100 staining human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human NFKBIZ / IKBZ
Mouse, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
NFKBIZ / IKBZ Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NFKBIZ (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NFKBIZ.
Select
Mouse Monoclonal [clone OTI1E8] (IgG1) to Human NFKBIZ / IKBZ
Human
Flo, WB
Unconjugated
100µl   0.58mg/ml   $345.00
Select
Mouse Monoclonal [clone OTI1E8] (IgG1) to Human NFKBIZ / IKBZ
Human
PE Conjugated
100µl   0.58mg/ml   $355.00
NFKBIZ / IKBZ Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NFKBIZ (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NFKBIZ.
Select
Mouse Monoclonal [clone OTI1E8] (IgG1) to Human NFKBIZ / IKBZ
Human
Flo, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal (IgG) to Human NFKBIZ / IKBZ
Human
ELISA, WB
Unconjugated
100µg   $375.00
Select
Rabbit Polyclonal (IgG) to Human NFKBIZ / IKBZ
Mouse, Rat, Human
WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
NFKBIZ / IKBZ Antibody
Select
Rabbit Polyclonal to Human NFKBIZ / IKBZ
Human
WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
NFKBIZ / IKBZ Antibody - Western blot analysis of extracts of various cell lines, using NFKBIZ antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
Rabbit Polyclonal (IgG) to Human NFKBIZ / IKBZ
Mouse, Rat, Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00

Viewing 1-25 of 31 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).