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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
NFAT5 is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | nuclear factor of activated T-cells 5, tonicity-responsive |
| Family/Subfamily: | Transcription factor |
| Synonyms: | NFAT5, NFAT-like protein 1, NFATZ, OREBP, KIAA0827, TonE-binding protein, TONEBP, Glutamine rich protein H65, NF-AT5, NFATL1 |
| Target Sequences: | NM_006599 NP_006590.1 O94916 |
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