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NEURL2

neuralized E3 ubiquitin protein ligase 2

Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.

Gene Name: neuralized E3 ubiquitin protein ligase 2
Synonyms: NEURL2, C20orf163, Neuralized-like 2 (Drosophila), Neuralized-like 2, OZZ, Ozz-E3, Neuralized-like protein 2, DJ337O18.6
Target Sequences: AW298115 Q9BR09 Q9BR09

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
NEURL2 (4)
No (4)
His (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Purified (1)
NEURL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.5 kDa
100 µg/$494
NEURL2 Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261; 20 µg/$298; 100 µg/$454; 500 µg/$1,177
NEURL2 Protein - Purified recombinant protein NEURL2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
31.5 kDa
20 µg/$1,107
NEURL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.5 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).