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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NEP / DDR1

discoidin domain receptor tyrosine kinase 1

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

Gene Name: discoidin domain receptor tyrosine kinase 1
Family/Subfamily: Protein Kinase , DDR/TKT
Synonyms: DDR1, Cell adhesion kinase, CD167, CD167a antigen, EDDR1, ENTRK4, Mammary carcinoma kinase 10, MCK10, NEP, PTK3, PTK3A, RTK6, Tyrosine-protein kinase CAK, CAK, DDR, Discoidin domain receptor 1, HGK2, MCK-10, NTRK4, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, TRKE, Tyrosine kinase DDR
Target Sequences: NM_013994 NP_054700.2 Q08345

Filtered by: None
Target
NEP / DDR1 (78)
Reactivity
Human (78)
Mouse (16)
Rat (17)
Bat (8)
Bovine (7)
Dog (7)
Horse (14)
Monkey (23)
Pig (15)
Application
IHC (44)
IHC-P (34)
WB (47)
Flo (6)
ELISA (22)
ICC (1)
IF (2)
IP (2)
Peptide-ELISA (4)
Host
rabbit (71)
mouse (7)
Isotype
IgG (26)
IgG1 (2)
IgG2b (1)
IgG2b,k (1)
Clonality
monoclonal mc (7)
polyclonal pc (71)
Clone
11C1024 (1)
1464CT339.1.54 (1)
2G4E12 (2)
4F2C12 (1)
Format
AP Conjugated (5)
APC (1)
APC Conjugated (7)
Azide-free (5)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (7)
Unconjugated (39)
Epitope
Internal (15)
C-Terminus (8)
aa17-47 (8)
aa568-829 (8)
N-Terminus (7)
pTyr513 (2)
260-340 aa, Internal (1)
450-530 aa (1)
740-820 aa (1)
Amino Acid: 602-681 (1)
Arg798 (1)
aa276-325 (1)
aa299-330 (1)
aa396-430 (1)
aa749-798 (1)
aa898-913 (1)
pTyr792 (1)
Publications
No (78)
Showing 1-25 of 78 results

IHC-plus™ NEP / DDR1 Antibody (C-Terminus) LS-A2854
Rabbit Polyclonal to Human NEP / DDR1
Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-DDR1 antibody IHC of human decidual cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NEP / DDR1 Antibody (clone 2G4E12) LS-B3861
Mouse Monoclonal [clone 2G4E12] (IgG1) to Human NEP / DDR1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-DDR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-DDR1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

IHC-plus™ NEP / DDR1 Antibody (N-Terminus) LS-A3436
Rabbit Polyclonal to Human NEP / DDR1
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-DDR1 antibody IHC of human decidual cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NEP / DDR1 Antibody (phospho-Tyr792) LS-C291485
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from A431 cells, using phospho-CD167a (Phospho-Tyr792) antibody.

NEP / DDR1 Antibody (450-530 aa) LS-C381401
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Phospho-DDR1 (Y513) antibody

NEP / DDR1 Antibody (aa17-47) LS-C97569
Rabbit Polyclonal to Human NEP / DDR1
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
DDR1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of anti-DDR1 Antibody antibody in placenta lysate. DDR1 (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

NEP / DDR1 Antibody (clone 11C1024) LS-C183823
Rabbit Monoclonal [clone 11C1024] (IgG) to Human NEP / DDR1
Mouse, Rat, Human, Monkey
ICC, IHC, IP, WB
Unconjugated
100µl  $575.00

NEP / DDR1 Antibody LS-C97571
Rabbit Polyclonal to Human NEP / DDR1
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MCK10 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of anti-MCK10 antibody in SK-BR-3 cell line lysates (35 ug/lane). MCK10 (arrow) was detected using the purified antibody.

IHC-plus™ NEP / DDR1 Antibody (aa17-47) LS-B15643
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Rat, Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50µl 1.44mg/ml  $425.00
: Formalin-Fixed, Paraffin-Embedded (FFPE), colon, at a concentration of 5 ug/ml.

NEP / DDR1 Antibody (aa17-47, Biotin) LS-C218915
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

NEP / DDR1 Antibody (aa17-47, FITC) LS-C218916
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

NEP / DDR1 Antibody (aa299-330) LS-C100877
Rabbit Polyclonal to Human NEP / DDR1
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
DDR1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of DDR1 Antibody with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

IHC-plus™ NEP / DDR1 Antibody (Internal) LS-A3437
Rabbit Polyclonal to Human NEP / DDR1
Pig, Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-DDR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NEP / DDR1 Antibody (clone 1464CT339.1.54) LS-C356272
Mouse Monoclonal [clone 1464CT339.1.54] (IgG2b,k) to Human NEP / DDR1
Human
Peptide-ELISA, WB
Unconjugated
400µl  $325.00
Western blot of lysate from MCF-7 cell line, using DDR1 antibody diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.

NEP / DDR1 Antibody (260-340 aa, Internal) LS-C383112
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Human
ELISA, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of DDR1 antibody

NEP / DDR1 Antibody (C-Terminus) LS-C358469
Rabbit Polyclonal to Human NEP / DDR1
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of CD167a expression in Jurkat (A); rat muscle (B) whole cell lysates.

IHC-plus™ NEP / DDR1 Antibody (Internal) LS-A2853
Rabbit Polyclonal to Human NEP / DDR1
Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-DDR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NEP / DDR1 Antibody (Internal, Biotin) LS-A103339
Rabbit Polyclonal to Human NEP / DDR1
Horse, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-DDR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NEP / DDR1 Antibody (Internal, FITC) LS-A103340
Rabbit Polyclonal to Human NEP / DDR1
Horse, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-DDR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NEP / DDR1 Antibody (Internal, APC) LS-A103338
Rabbit Polyclonal to Human NEP / DDR1
Horse, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-DDR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ NEP / DDR1 Antibody (Internal, AP) LS-A103337
Rabbit Polyclonal to Human NEP / DDR1
Horse, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-DDR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NEP / DDR1 Antibody (clone 4F2C12) LS-C682623
Mouse Monoclonal [clone 4F2C12] (IgG2b) to Human NEP / DDR1
Human
ELISA, Flo, WB
Unconjugated
100µl  $365.00

NEP / DDR1 Antibody LS-C801451
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

NEP / DDR1 Antibody (phospho-Tyr513) LS-C800730
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

NEP / DDR1 Antibody (phospho-Tyr513) LS-C800754
Rabbit Polyclonal (IgG) to Human NEP / DDR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image
Showing 1-25 of 78 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).