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NEK6
NIMA-related kinase 6
NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain. The protein is believed to regulate chromatin condensation in mammalian cells via phosphorylation of histones H1 and H3, and it has been shown to phosphorylate ribosomal S6 protein kinase (S6K1) and serum and glucocorticoid induced protein kinase (SGK1), which regulate diverse cellular processes. The protein also has been shown to bind NEK9, another NIMA-related kinase which regulates chromosome alignment and segregation. At least three mRNA transcripts have been identified, 1.6-, 2.6-, and 9.5-kb. The NEK6 gene is localized to 9q33-34, a region at which the loss of heterozygosity is associated with transitional cell carcinomas.
| Gene Name: | NIMA-related kinase 6 |
| Family/Subfamily: | Protein Kinase , NEK |
| Synonyms: | NEK6, NIMA-related kinase 6, Protein kinase SID6-1512, NimA-related protein kinase 6, SID6-1512 |
| Target Sequences: | NM_014397 NP_055212.2 Q9HC98 |
Publications (1)
1
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. Takeno A, Takemasa I, Doki Y, Yamasaki M, Miyata H, Takiguchi S, Fujiwara Y, Matsubara K, Monden M. British journal of cancer. 2008 99:1307-15.
[PubMed:18827816]
[PMC:PMC2570518]
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NEK6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Cancer
Fast Shipping
NEK6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
NEK6 Mouse anti-Human Monoclonal (OTI5D7) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NEK6 Mouse anti-Human Monoclonal (Carrier-free) (OTI5D7) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NEK6 Mouse anti-Human Monoclonal (OTI5B9) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NEK6 Mouse anti-Human Monoclonal (Carrier-free) (OTI5B9) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
NEK6 Mouse anti-Human Monoclonal (OTI8G5) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NEK6 Mouse anti-Human Monoclonal (Carrier-free) (OTI8G5) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
NEK6 Mouse anti-Human Monoclonal (OTI2H7) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$434
NEK6 Mouse anti-Human Monoclonal (Carrier-free) (OTI2H7) Antibody
Human
IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
NEK6 Rabbit anti-Mouse Polyclonal (aa251-280) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
NEK6 Rabbit anti-Mouse Polyclonal (aa251-280) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
NEK6 Rabbit anti-Human Polyclonal (aa251-280) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
NEK6 Rabbit anti-Human Polyclonal (aa251-280) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
NEK6 Rabbit anti-Human Polyclonal (aa251-280) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
NEK6 Rabbit anti-Human Polyclonal (aa251-280) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
NEK6 Rabbit anti-Human Polyclonal (aa251-280) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
NEK6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
NEK6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
NEK6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NEK6 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
WB
Unconjugated
100 µl/$424
NEK6 Rabbit anti-Human Polyclonal (aa38-87) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
NEK6 Rabbit anti-Human Polyclonal (aa38-87) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
NEK6 Rabbit anti-Human Polyclonal (aa38-87) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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