NEDD8

neural precursor cell expressed, developmentally down-regulated 8

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

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Products

Proteins (8)

Type

Recombinant (8)

Target

NEDD8 (8)

Publications

No (8)

Tag

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (2)

His (1)

His, N-Terminal (1)

Species

Human (8)

Source

E. coli (6)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (4)

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Human NEDD8 Protein (Recombinant 6His-SUMO, N-terminus) (Met1-Gly76) - LS-G39740

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.9kD

Price:

10 µg/$225; 50 µg/$243; 500 µg/$395; 1 mg/$505

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Human NEDD8 Protein (Recombinant GST, N-terminus) - LS-G56709

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human NEDD8 Protein (Recombinant GST, N-terminus) (aa1-81) - LS-G59372

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NEDD8 Protein (Recombinant GST) (Full Length) - LS-G29489

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

35.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NEDD8 Protein (Recombinant His, N-Terminal) - LS-G144217

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

8.9 kDa

Price:

50 µg/$419

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Human NEDD8 Protein (Recombinant 6His, N-terminus) (Met1-Gly76) - LS-G138548

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.9 kDa

Price:

10 µg/$226; 50 µg/$244

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Human NEDD8 Protein (Recombinant) - LS-G146179

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

8.6 kDa

Price:

10 µg/$225; 50 µg/$253

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Human NEDD8 Protein (Recombinant His) - LS-G3502

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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