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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NEDD4L / NEDD4-2

neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2.

Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Synonyms: NEDD4L, HNEDD4-2, KIAA0439, NEDD4-2, RSP5, NEDD4.2, NEDL3, Ubiquitin-protein ligase Rsp5
Target Sequences: AB007899 BAA23711.1 Q96PU5

Filtered By: None
Target
NEDD4L / NEDD4-2 (26)
Reactivity
Human (20)
Mouse (19)
Rat (7)
Bat (4)
Bovine (8)
Chicken (4)
Chimpanzee (3)
Dog (7)
Gibbon (3)
Guinea pig (7)
Horse (7)
Monkey (4)
Orangutan (3)
Pig (7)
Rabbit (5)
Xenopus (4)
Application
IHC (8)
IHC-P (4)
WB (20)
ELISA (12)
IF (3)
IP (3)
Host
rabbit (26)
Isotype
IgG (19)
Clonality
polyclonal pc (26)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
Epitope
aa576-604 (8)
aa431-480 (4)
aa275-325 (2)
aa225-275 (1)
aa425-475 (1)
Publications
No (26)
Showing 1-25 of 26 results

NEDD4L / NEDD4-2 Antibody (aa225-275) IHC-plus™ LS-B12343
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Rabbit, Mouse, Bovine, Pig, Human
IF IHC IHC-P IP WB
Unconjugated
50µl 0.2mg/ml  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

NEDD4L / NEDD4-2 Antibody (aa275-325) IHC-plus™ LS-B12344
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Human
IF IHC IHC-P IP WB
Unconjugated
50µl 0.2mg/ml  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

NEDD4L / NEDD4-2 Antibody (aa275-325) IHC-plus™ LS-B12408
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Human
IF IHC IHC-P
Unconjugated
50µl  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

NEDD4L / NEDD4-2 Antibody LS-C751955
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Human
ELISA IHC WB
Unconjugated
100µg  $355.00

NEDD4L / NEDD4-2 Antibody LS-C409621
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Immunohistochemistry of paraffin-embedded human prostate.
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Immunohistochemistry of paraffin-embedded human prostate.

NEDD4L / NEDD4-2 Antibody LS-C668117
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Western blot Image
Immunohistochemistry - Paraffin Image
Western blot Image

NEDD4L / NEDD4-2 Antibody LS-C405200
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human prostate cancer using NEDD4L Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human prostate cancer using NEDD4L Polyclonal Antibody at dilution of 1:50.

NEDD4L / NEDD4-2 Antibody LS-C401887
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using NEDD4L Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human liver cancer using NEDD4L Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human liver cancer using NEDD4L Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human liver cancer using NEDD4L Polyclonal Antibody at dilution of 1:60.

NEDD4L / NEDD4-2 Antibody (aa576-604) LS-C323281
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Human
ELISA WB
Unconjugated
200µl  $530.00

NEDD4L / NEDD4-2 Antibody (aa576-604, Biotin) LS-C264180
Rabbit Polyclonal (IgG) to Mouse NEDD4L / NEDD4-2
Mouse
ELISA WB
Biotin Conjugated
200µl  $680.00

NEDD4L / NEDD4-2 Antibody (aa576-604, FITC) LS-C264181
Rabbit Polyclonal (IgG) to Mouse NEDD4L / NEDD4-2
Mouse
ELISA WB
FITC Conjugated
200µl  $680.00

NEDD4L / NEDD4-2 Antibody (aa576-604, APC) LS-C264178
Rabbit Polyclonal (IgG) to Mouse NEDD4L / NEDD4-2
Mouse
ELISA WB
APC Conjugated
200µl  $680.00

NEDD4L / NEDD4-2 Antibody (aa576-604, AP) LS-C264179
Rabbit Polyclonal (IgG) to Mouse NEDD4L / NEDD4-2
Mouse
ELISA WB
AP Conjugated
200µl  $680.00

NEDD4L / NEDD4-2 Antibody (aa576-604, Azide-free, HRP) LS-C264182
Rabbit Polyclonal (IgG) to Mouse NEDD4L / NEDD4-2
Mouse
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

NEDD4L / NEDD4-2 Antibody (aa576-604, PE) LS-C264183
Rabbit Polyclonal (IgG) to Mouse NEDD4L / NEDD4-2
Mouse
ELISA WB
PE Conjugated
200µl  $680.00

NEDD4L / NEDD4-2 Antibody LS-C662725
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Human
ELISA WB
Unconjugated
100µg  $325.00
Western blot - Anti-NEDD4-2 Picoband antibody
Western blot - Anti-NEDD4-2 Picoband antibody

NEDD4L / NEDD4-2 Antibody LS-C671483
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Positive Western Blot detected in 293 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate. All lanes: NEDD4L antibody at 3 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 112, 105, 101, 99, 111, 110, 97 KDa. Observed band size: 112 KDa
Positive Western Blot detected in 293 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate. All lanes: NEDD4L antibody at 3 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 112, 105, 101, 99, 111, 110, 97 KDa. Observed band size: 112 KDa

NEDD4L / NEDD4-2 Antibody (HRP) LS-C671484
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

NEDD4L / NEDD4-2 Antibody (Biotin) LS-C671485
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Human
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

NEDD4L / NEDD4-2 Antibody (aa425-475) LS-C289248
Rabbit Polyclonal (IgG) to Human NEDD4L / NEDD4-2
Mouse, Dog, Guinea pig, Bovine, Horse, Human
IP WB
Unconjugated
100µl 0.2mg/ml  $395.00

NEDD4L / NEDD4-2 Antibody (aa431-480) LS-C110766
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
50µg  $365.00
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NEDD4L / NEDD4-2 Antibody (aa431-480, HRP) LS-C444801
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NEDD4L / NEDD4-2 Antibody (aa431-480, Biotin) LS-C444582
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NEDD4L / NEDD4-2 Antibody (aa431-480, FITC) LS-C444800
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
NEDD4L antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NEDD4L / NEDD4-2 Antibody (aa576-604) LS-C164819
Rabbit Polyclonal to Human NEDD4L / NEDD4-2
Mouse, Human
WB
Unconjugated
400µl  $305.00
NEDD4L Antibody western blot of mouse brain tissue lysates (35 ug/lane). The NEDD4L antibody detected the NEDD4L protein (arrow).
NEDD4L Antibody western blot of mouse brain tissue lysates (35 ug/lane). The NEDD4L antibody detected the NEDD4L protein (arrow).
Showing 1-25 of 26 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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