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NECAP1

NECAP endocytosis associated 1

NECAP1 is a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

Gene Name: NECAP endocytosis associated 1
Synonyms: NECAP1, DKFZP566B183, NECAP-1, NECAP endocytosis associated 1
Target Sequences: NM_015509 NP_056324.2 Q8NC96

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).