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NECAP1 is a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Gene Name: | NECAP endocytosis associated 1 |
Synonyms: | NECAP1, DKFZP566B183, NECAP-1, NECAP endocytosis associated 1 |
Target Sequences: | NM_015509 NP_056324.2 Q8NC96 |
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