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NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Synonyms: NDUFV1, CI-51K, CI-51kD, Complex I 51 kda subunit, CI51KD, UQOR1, Complex I 51kDa subunit, Complex I-51kD
Target Sequences: NM_007103 NP_009034.2 P49821

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
NDUFV1 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
NDUFV1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
50.82 kDa
100 µg/$494
NDUFV1 Protein - 12.5% SDS-PAGE of human NDUFV1 stained with Coomassie Blue
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Wheat Germ Extract
GST
77.2 kDa
2 µg/$439
NDUFV1 Protein - Purified recombinant protein NDUFV1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
48.5 kDa
20 µg/$1,107
NDUFV1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NDUFV1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
50.82 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).