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NDUFB2 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I.
Gene Name: | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa |
Synonyms: | NDUFB2, AGGG, Complex I AGGG subunit, Complex I-AGGG, CI-AGGG |
Target Sequences: | NM_004546 NP_004537.1 O95178 |
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