NDST1

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

NDST1 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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NDST1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118524

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.7 kDa

Price:

100 µg/$710

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Human NDST1 Protein (Recombinant His-SUMO) (aa40-556) - LS-G20999

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

73.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human NDST1 Protein (Recombinant GST) (Full Length) - LS-G28945

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

127.3 kDa

Price:

2 µg/$439

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Human NDST1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76413

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.7 kDa

Price:

20 µg/$215

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Human NDST1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65857

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.7 kDa

Price:

20 µg/$1,107

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Human NDST1 Protein (Recombinant GST, N-terminus) (aa38-136) - LS-G58915

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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