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NCS1 / Neuronal Calcium Sensor

neuronal calcium sensor 1

Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.

Gene Name: neuronal calcium sensor 1
Synonyms: NCS1, Frequenin (Drosophila) homolog, FREQ, FLUP, Frequenin homolog, Neuronal calcium sensor 1, Frequenin homolog (Drosophila), Frequenin-like protein, NCS-1
Target Sequences: NM_014286 NP_055101.2 P62166

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Products
Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
NCS1 / Neuronal Calcium Sensor (9)
No (9)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (5)
Human (7)
293T Cells (2)
E. coli (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
NCS1 / Neuronal Calcium Sensor Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
NCS1 / Neuronal Calcium Sensor Protein - Purified recombinant protein NCS1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21.7 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
21.7 kDa
20 µg/$150
NCS1 / Neuronal Calcium Sensor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
19.5 kDa
20 µg/$150
NCS1 / Neuronal Calcium Sensor Protein - 12.5% SDS-PAGE of human FREQ stained with Coomassie Blue
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Wheat Germ Extract
GST
46.64 kDa
2 µg/$439
NCS1 / Neuronal Calcium Sensor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.7 kDa
100 µg/$494
NCS1 / Neuronal Calcium Sensor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
19.5 kDa
100 µg/$494
NCS1 / Neuronal Calcium Sensor Protein
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E. coli
His
100 µg/$342; 500 µg/$641; 20 µg/$254
NCS1 / Neuronal Calcium Sensor Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-9 of 9 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).