NCOA6 / ASC-2

nuclear receptor coactivator 6

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

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Products

Proteins (2)

Type

Recombinant (2)

Target

NCOA6 / ASC-2 (2)

Publications

No (2)

Tag

GST, N-terminus (1)

His-GST, N-terminus (1)

Species

Human (1)

Mouse (1)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Mouse NCOA6 / ASC-2 Protein (Recombinant His-GST, N-terminus) (Ala168-Thr374) - LS-G133251

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

52.7kDa

Price:

10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human NCOA6 / ASC-2 Protein (Recombinant GST, N-terminus) (aa1954-2063) - LS-G61913

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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