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NCOA3 / SRC-3 / AIB1

nuclear receptor coactivator 3

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.

Gene Name: nuclear receptor coactivator 3
Synonyms: NCOA3, ACTR, AIB1, BHLHe42, CAGH16, CBP-interacting protein, CTG26, AIB-1, P/CIP, TNRC14, TRAM-1, Nuclear receptor coactivator 3, PCIP, RAC-3, SRC3, TNRC16, KAT13B, NCoA-3, SRC-3
Target Sequences: NM_006534 NP_006525.2 Q9Y6Q9

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
NCOA3 / SRC-3 / AIB1 (8)
No (8)
GST, N-terminus (1)
His (1)
His-S (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (5)
Rat (1)
293T Cells (2)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Low endotoxin level (1)
NCOA3 / SRC-3 / AIB1 Protein - Recombinant Nuclear Receptor Coactivator 3 By SDS-PAGE
Select
E. coli
His-T7
35.3 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
NCOA3 / SRC-3 / AIB1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NCOA3 / SRC-3 / AIB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
155.3 kDa
20 µg/$215
NCOA3 / SRC-3 / AIB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
154.7 kDa
20 µg/$215
NCOA3 / SRC-3 / AIB1 Protein - Recombinant Nuclear Receptor Coactivator 3 By SDS-PAGE
Select
E. coli
His-S
38.0 kDa
10 µg/$287; 50 µg/$477; 100 µg/$762; 200 µg/$952; 1 mg/$2,083; 500 µg/$1,613; 5 mg/$3,333; 2 mg/$2,272
NCOA3 / SRC-3 / AIB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
155.3 kDa
100 µg/$710
NCOA3 / SRC-3 / AIB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
154.7 kDa
100 µg/$710
Select
E. coli
109 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.1 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).