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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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NCOA2 / TIF2

nuclear receptor coactivator 2

The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997 [PubMed 9111344]).

Gene Name: nuclear receptor coactivator 2
Synonyms: NCOA2, BHLHe75, KAT13C, NCoA-2, HTIF2, SRC2, TIF2, Nuclear receptor coactivator 2
Target Sequences: NM_006540 NP_006531.1 Q15596

Viewing 1-25 of 39 items
NCOA2 / TIF2 Antibody - Anti-NCOA2 / TIF2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
IHC, IHC-P
Unconjugated
50µl   $425.00
NCOA2 / TIF2 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   1mg/ml   $425.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
HRP Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
Biotin Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
FITC Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
Unconjugated, Azide-free
100µl   $725.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
AP Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
APC Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
PE Conjugated
100µl   $905.00
NCOA2 / TIF2 Antibody - Immunohistochemistry of paraffin-embedded rat brain using NCOA2 antibodyat dilution of 1:100 (40x lens).
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl   $275.00; 100µl   $355.00; 200µl   $455.00
Select
Mouse Monoclonal (IgG1,k) to Human NCOA2 / TIF2
Human
IP, WB
Unconjugated
500µl   $680.00
NCOA2 / TIF2 Antibody - Anti-NCOA2 Antibody (C-Term) at 1:2000 dilution + U-2OS whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 159 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
Rabbit Polyclonal to Human NCOA2 / TIF2
Human
Peptide-ELISA, WB
Unconjugated
200µl   $325.00
NCOA2 / TIF2 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NCoA2 (Phospho-Ser736) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
ELISA, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
NCOA2 / TIF2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NCoA2 antibody.
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
ELISA, IHC
Unconjugated
100µg   $305.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
IHC, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Mouse, Human
IHC, IHC-Fr
Unconjugated
100µg   $530.00
Select
Mouse Monoclonal [clone 2615C1a] (IgG1) to Human NCOA2 / TIF2
Mouse, Rat, Human
DB, WB
Unconjugated
100µg   $560.00
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Human
IP, WB
Unconjugated
100µl   1mg/ml   $395.00
NCOA2 / TIF2 Antibody - Detection of Mouse SRC2 by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-SRC2 antibody used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
Rabbit Polyclonal (IgG) to Human NCOA2 / TIF2
Mouse, Human
IP, WB
Unconjugated
100µl   1mg/ml   $395.00
NCOA2 / TIF2 Antibody - Anti-NCOA2 Antibody (Center) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 159 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
Rabbit Polyclonal to Human NCOA2 / TIF2
Human
Peptide-ELISA, WB
Unconjugated
200µl   $325.00
Select
Mouse Monoclonal (IgG1) to Human NCOA2 / TIF2
Mouse, Rat, Human
WB
Unconjugated
100µg   $590.00

Viewing 1-25 of 39 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).