NCOA1 / SRC-1

nuclear receptor coactivator 1

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.

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Products

Antibodies (22)

Type

Primary (22)

Target

NCOA1 / SRC-1 (22)

Reactivity

Human (22)

Mouse (7)

Rat (6)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Monkey (5)

Application

IHC (5)

IHC-P (2)

WB (16)

DB (1)

ELISA (6)

IF (2)

IP (3)

Peptide-ELISA (1)

Host

rabbit (18)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (10)

IgG1 (1)

IgG2b (2)

Clonality

monoclonal mc (4)

polyclonal pc (18)

Clone

1135 (1)

3532C6a (1)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (16)

Epitope

aa611-660 (4)

aa477-947 (2)

aa1400-C-term (1)

aa186-214 (1)

aa594-625 (1)

aa600-650 (1)

aa614-826 (1)

Publications

No (21)

Yes (1)

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IHC-plus™ NCOA1 / SRC-1 Antibody (aa477-947, clone 1135) LS-B1702

(5.0) Rating

(1) Publication(s)

Antibody:

NCOA1 / SRC-1 Mouse anti-Human Monoclonal (aa477-947) (1135) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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NCOA1 / SRC-1 Antibody (aa186-214) LS-C100196

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa186-214) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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NCOA1 / SRC-1 Antibody LS-C331277

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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NCOA1 / SRC-1 Antibody LS-C752037

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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NCOA1 / SRC-1 Antibody (aa600-650) LS-C287239

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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NCOA1 / SRC-1 Antibody LS-C678772

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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NCOA1 / SRC-1 Antibody (HRP) LS-C678773

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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NCOA1 / SRC-1 Antibody (Biotin) LS-C678771

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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NCOA1 / SRC-1 Antibody (FITC) LS-C678774

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

NCOA1 / SRC-1 Antibody LS-C778829

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

NCOA1 / SRC-1 Antibody (aa1400-C-term) LS-C286207

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa1400-C-term) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$514

Select

NCOA1 / SRC-1 Antibody LS-C804231

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NCOA1 / SRC-1 Antibody LS-C832877

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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NCOA1 / SRC-1 Antibody (aa477-947) LS-C83541

Antibody:

NCOA1 / SRC-1 Mouse anti-Human Monoclonal (aa477-947) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$563

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NCOA1 / SRC-1 Antibody LS-C75958

Antibody:

NCOA1 / SRC-1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$558

Select

NCOA1 / SRC-1 Antibody (clone 3532C6a) LS-C184632

Antibody:

NCOA1 / SRC-1 Mouse anti-Human Monoclonal (3532C6a) Antibody

Reactivity:

Human

Applications:

DB

Format:

Unconjugated

Price:

50 µg/$474

Select

NCOA1 / SRC-1 Antibody (aa611-660) LS-C109852

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa611-660) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

NCOA1 / SRC-1 Antibody (aa611-660, HRP) LS-C430416

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa611-660) (HRP) Antibody

Reactivity:

Dog, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

NCOA1 / SRC-1 Antibody (aa611-660, Biotin) LS-C430414

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa611-660) (Biotin) Antibody

Reactivity:

Dog, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

NCOA1 / SRC-1 Antibody (aa611-660, FITC) LS-C430415

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa611-660) (FITC) Antibody

Reactivity:

Dog, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

NCOA1 / SRC-1 Antibody (aa594-625) LS-C161489

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa594-625) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

NCOA1 / SRC-1 Antibody (aa614-826) LS-C357604

Antibody:

NCOA1 / SRC-1 Rabbit anti-Human Polyclonal (aa614-826) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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