NCK1 / NCK

NCK adaptor protein 1

Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.

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Products

Proteins (11)

Type

Over-Expression Lysate (4)

Recombinant (7)

Target

NCK1 / NCK (11)

Publications

No (11)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

Myc-DDK (Flag) (4)

Species

Human (9)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human NCK1 / NCK Protein (Recombinant 6His, N-terminus) (Met1-Ser377) - LS-G39663

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human NCK1 / NCK Protein (Recombinant GST, N-terminus) (aa185-294) - LS-G59353

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NCK1 / NCK Protein (Recombinant His) (aa2-377) - LS-G25046

Source:

E. coli

Tag:

His

Molecular Weight:

46.4 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Human NCK1 / NCK Protein (Recombinant GST) (Full Length) - LS-G29449

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NCK1 / NCK Protein (Recombinant His, N-Terminal) - LS-G145157

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

42.7 kDa

Price:

50 µg/$419

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NCK1 / NCK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115495

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.7 kDa

Price:

100 µg/$494

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NCK1 / NCK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130876

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36 kDa

Price:

100 µg/$494

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Human NCK1 / NCK Protein (Recombinant His) - LS-G811

Source:

E. coli

Tag:

His

Price:

100 µg/$342; 500 µg/$641; 20 µg/$254

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Human NCK1 / NCK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75436

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36 kDa

Price:

20 µg/$150

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Human NCK1 / NCK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75434

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.7 kDa

Price:

20 µg/$150

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Human NCK1 / NCK Protein (Recombinant 6His, N-terminus) (Met1-Ser377) - LS-G139068

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.0 kDa

Price:

10 µg/$281; 50 µg/$389

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