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Locations
Orders Processing,
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Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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NBR1
neighbor of BRCA1 gene 1
NBR1 was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
| Gene Name: | neighbor of BRCA1 gene 1 |
| Synonyms: | NBR1, 1A1-3B, 1A13B, CA125, M17S2, MIG19, Migration-inducing protein 19, Neighbor of BRCA1 gene 1, KIAA0049, Next to BRCA1 gene 1 protein, Protein 1A1-3B |
| Target Sequences: | NM_005899 NP_005890.2 Q14596 |
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