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NAV1 belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
Gene Name: | neuron navigator 1 |
Synonyms: | NAV1, KIAA1213, Neuron navigator 1, POMFIL3, Steerin-1, STEERIN1, Neuron navigator-1, Unc-53 homolog 1, UNC53H1, KIAA1151 |
Target Sequences: | NM_020443 |
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